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Comparing COVID-19 Vaccines

Updated On Jan 25, 2022

The World Health Organisation gathered specialists from several organisations and internal divisions to "explore easy-to-pronounce and non-stigmatizing labels" in an effort to make it simpler for the public and media to discuss variations. Which is why the numerous variations now have Greek Alphabet designations, at least for those that WHO has labelled Variants of Concern (VOC) and Variants of Interest (VOI) (VOI). In the United States, the Delta variation is the only one classed as a VOC, and no VOIs are now recognised.

Vaccines from Pfizer-BioNTech, Moderna, and Johnson & Johnson are being used. Pfizer-BioNTech or Moderna vaccines are recommended by the Centers for Disease Control and Prevention (CDC). Booster injections are also suggested, and adults can pick a different vaccination for their booster than the one they started with using a "mix-and-match" strategy. To find out and know more about COVID-19 vaccines, read on.

Comparing COVID-19 Vaccines


In August 2021, Pfizer-BioNTech became the first COVID-19 vaccine to be approved by the Food and Drug Administration (FDA) for persons aged 16 and above. It was also the first COVID-19 vaccine to be granted an FDA Emergency Use Authorisation (EUA) in December 2020, after the business reported that the vaccination was very successful in avoiding symptomatic sickness. Vaccination using messenger RNA (mRNA) is a relatively new approach that uses messenger RNA (mRNA). It must be kept at freezing temperatures, making it more difficult to deliver than certain other vaccinations.


Moderna's vaccine received emergency approval in the United States in December 2020, just a week after Pfizer's vaccine. Moderna employs the same mRNA technology as Pfizer and has similar symptomatic illness prevention effectiveness. It should also be maintained at a temperature below freezing. The FDA authorised a third dosage of the Moderna vaccine in mid-August for select immunocompromised people, such as solid organ transplant patients and those with disorders that make them equally vulnerable to infections and other ailments.

Johnson & Johnson

When the FDA approved Johnson & Johnson's vaccine in February 2021, it was hailed as a game-changer due to its one-shot approach, which made it easier to market and administer to individuals who felt it to be the most convenient of the three vaccinations available in the United States. The J&J shot, on the other hand, has been received by a far smaller number of people.

The CDC endorsed a preference for Pfizer and Moderna in December, citing factors such as worry over uncommon blood clots related to it. This is a carrier, or virus vector, vaccine, as opposed to the mRNA vaccines.

Russia’s Sputnik V Vaccine

Sputnik V had an effectiveness rate of 92 percent after the second dosage, according to Russia's National Research Center for Epidemiology and Microbiology on November 11, 2020. The vaccine was licensed for use in Russia in August 2020, before even starting a Phase III research.

During the current Phase III investigation, the revised effectiveness assessment was based on a first interim analysis 21 days following the initial injection. According to fresh preliminary statistics released on November 24, the group claimed 95 percent effectiveness. They announced an effectiveness of 91.4 percent on December 14, 2020. It also provided AstraZeneca one of its two human adenoviral vectors to boost the vaccine's potency.


Our first and most important line of defence has always been and will always be public health, which entails leadership and a culture of understanding and acceptance of drastic measures when the circumstance necessitates them. Widespread testing, both at home and in public areas such as schools, workplaces, and large public events, as well as thorough contact tracking and notification of those who have been exposed, are critical. To avoid viral propagation in the case of new outbreaks, strict public health measures like mask use, increased ventilation, social distance, obligatory quarantine and isolation, and, if required, lockdowns must be implemented.

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Disclaimer: This article is issued in the general public interest and meant for general information purposes only. Readers are advised not to rely on the contents of the article as conclusive in nature and should research further or consult an expert in this regard.

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